Which movie holds the record for the highest opening weekend in the mcu?

The only source supplied is a general overview of the Marvel Cinematic Universe and a list of its films. It details the franchise’s history, production, and total gross, but it does not include any box‑office statistics, such as opening weekend earnings, for individual movies. Therefore, based on the evidence at hand, we cannot identify a specific film that holds the record for the highest opening weekend within the MCU. If you need that information, you would need to consult a source that provides detailed box‑office data for each MCU release.