Do gta online characters interact with story mode characters?

Grand Theft Auto Online is described as the online component of Grand Theft Auto V, where players create a customisable silent protagonist to explore the open world of San Andreas. The game is designed for up to thirty players to roam the same world, but the online component is separate from the single‑player story campaign. In the official description, there is no mention of online players or characters interacting with the pre‑created story mode characters such as Michael, Franklin, or Trevor. Consequently, the online experience is independent; players cannot encounter or engage with the story mode characters in any official capacity. Therefore, based on the available evidence, GTA Online characters do not interact with the story mode characters.